Which of the following statements about Okazaki fragments in E. coli is true?

Question: Part E Which of the following statements about Okazaki fragments in E. coli is true?

1. They are synthesized in the 3′ to 5′ direction.
2. They are formed on the lagging strand of DNA.
3. They are usually 50 to 500 bases long
4. They are sealed together by the action of helicase.

Second question (Part E):

The answer will be they are formed on the lagging strand of DNA (Second option).

Explanation:

DNA synthesis always occurs in the 5′ to 3′ direction so Okazaki fragments will also be synthesized in the 5′ to 3′ direction. So, we can ignore first option. They range from 1000-2000 nucleotides in E. coli. So, we can ignore third option. They are sealed by DNA ligase. So, we can ignore last option. Discontinuous synthesis of short fragments of DNA in the lagging strand is known as Okazaki fragments. So, correct answer will be second option.